8-19

Diels-Alder Reaction

The Diels–Alder reaction is a concerted reaction: the addition of the electrophile and the nucleophile occurs in a singl...
18-13

Claisen-Schmidt Condensation

A method for obtaining one product from cross aldol addition The condensation of an aromatic aldehyde (without α-hydroge...
6-11

Ozonolysis of alkenes

Ozonolysis is an example of oxidative cleavage —an oxidation reaction that cleaves the reactant into pieces. Mechanism f...
18-11

Aldol condensation

When the product of an aldol addition is dehydrated, the overall reaction is called an aldol condensation. Unlike alcoho...
18-10

Aldol addtion

Connecting the α-carbon of one with the carbonyl carbon of the other. The carbonyl carbon of an aldehyde or ketone is an...
b. Alkynes

Alkylation using acetylide ions

Alkylation using a ACETYLIDE ion.Acidity of Terminal AlkynesTerminal alkynes are more acidic than alkenes and alkanes.Ka...
18. α-Carbon

Alkylation of the β-carbon

Michael reaction1,4-addition is called conjugate addition. Using enolate ions as nucleophiles in conjugate addition, thi...
b. Alkynes

Hydroboration and Oxymercuration of Alkynes

Hydroboration and Oxymercuration of AlkynesHydroboration–oxidation of AlkyneKametonBH3 or R2BH (in THF) adds to alkynes ...
18. α-Carbon

Alkylation of the α-carbon

Alkylating the α-carbon via enolate formationAlkylating the α-carbon via enolate formationPutting an alkyl group on the ...
06. Alkenes

Alcohol synthesis from Alkenes

Alcohol synthesis from AlkenesMarkovnikov’s ruleThe electrophile adds preferentially to the sp2 carbon bonded to the mos...